### Multiple Myeloma and Dental Health Multiple myeloma is a rare cancer that affects plasma cells, a type of white blood cell found mainly in the bone marrow. These cells play a crucial role in your body's immune system. When they become cancerous, they can interfere with healthy cells in various parts of the body, including the bones. #### Dental Problems as a Sign In about 30% of cases, multiple myeloma can affect the mouth cavities and facial bones like the jaw. Dental problems can sometimes be the first sign of the disease. Symptoms may include jaw pain, loose teeth, or other dental issues. If you experience these symptoms, it's essential to inform your dentist or doctor for further evaluation. #### Treatment Side Effects One of the treatments for bone damage caused by multiple myeloma is bisphosphonates. These drugs help slow down bone breakdown and are usually administered once a month through a vein or by mouth. However, bisphosphonates can have a rare but serious side effect called osteonecrosis of the jaw (ONJ). This condition occurs when the bone cells in your jawbone break down or die, leading to exposed bone in your mouth. #### Managing ONJ The risk of developing ONJ is higher if you take bisphosphonates through your veins and can be triggered by dental surgery or tooth extractions. Symptoms of ONJ can range from mild to severe and may include pain, swelling, and exposed bone. If you develop ONJ, your doctor may stop your treatment and put you on a specific treatment plan. #### Preventive Measures If you are diagnosed with multiple myeloma and plan to undergo dental procedures, inform your doctor. It's best to complete any necessary dental work before starting bisphosphonate treatment. Routine dental procedures like fillings, root canals, and crowns generally do not cause ONJ. Maintaining good oral hygiene can also help prevent dental problems. In summary, while multiple myeloma primarily affects the bones, it can also lead to dental issues. Early detection and proper management can help mitigate these problems.