What are the symptoms and management options for Charcot-Marie-Tooth disease?

Charcot-Marie-Tooth (CMT) disease is a genetic disorder that affects the nerves outside the brain and spinal cord. It primarily impacts the feet and hands, leading to muscle weakness and sensory problems. Symptoms often start in childhood or adolescence and include high foot arches, hammertoes, difficulty walking, foot drop, muscle loss in the lower legs, numbness, and balance issues. As the disease progresses, it may also affect the hands and arms. Although there is no cure for CMT, it can be managed with physical therapy, braces, orthopedic devices, and sometimes surgery. Regular foot care, including checking for blisters and calluses, keeping nails trimmed, and wearing appropriate shoes, is crucial. Support groups like the Charcot-Marie-Tooth Association and the Muscular Dystrophy Association can provide additional help and resources.