Antidepressants are primarily used to treat depression, but they can also be effective in treating certain skin conditions. For example, some skin conditions are exacerbated by stress and anxiety, which antidepressants can help alleviate. Additionally, certain antidepressants have anti-inflammatory properties that can help reduce symptoms of skin conditions like eczema and psoriasis. However, it's important to consult a healthcare provider before using antidepressants for skin conditions, as they can have side effects and may not be suitable for everyone.