### Managing Side Effects of Psoriatic Arthritis and Psoriasis Treatments Medications for psoriatic arthritis (PsA) and psoriasis can sometimes cause unexpected side effects. Here’s what you need to know and how to manage them: #### Biologic Drugs Biologic drugs target specific proteins in your immune system to reduce inflammation. However, they can cause skin reactions. Rarely, they may lead to a condition called “lupus-like syndrome,” which includes symptoms like swollen joints and a rash that worsens in sunlight. If you experience these symptoms, contact your doctor immediately. They may switch you to a different medication. #### Steroids Steroids are used to treat inflammation. Topical steroids can cause acne or red sores, and prolonged use can thin your skin. Oral steroids can also thin your skin and cause bruises. Stopping oral steroids suddenly can lead to severe psoriasis flare-ups. Steroid shots may cause skin discoloration or pain at the injection site. Use the lowest effective dose and follow your doctor’s instructions. #### Antimalarials Some people with PsA take antimalarial drugs like hydroxychloroquine (Plaquenil). These can cause severe psoriasis flare-ups, rashes, dark spots, hair loss, and muscle weakness. If you notice these side effects, inform your doctor. #### Topical Treatments Topical treatments for mild to moderate psoriasis can cause skin reactions. Use them as directed and switch to a more soothing cream if they dry your skin. #### Light Therapy Light therapy can help treat psoriasis plaques but may cause side effects like skin dryness or increased sun sensitivity. Moisturize regularly and apply sunscreen after phototherapy. Avoid commercial tanning beds. #### Exercise Exercise is beneficial for PsA and psoriasis but can sometimes cause joint or muscle soreness. If you experience sharp pain, you may have injured yourself. Slow down and build your endurance gradually. A physical therapist can help you create a safe exercise plan. Always consult your healthcare provider for personalized advice and treatment adjustments.