Causes and Care Recommendations for Infant Jaundice and Cholestasis

### Causes and care recommendations for jaundice and cholestasis in infants Infantile jaundice and cholestasis are common liver problems in newborns and infants. Jaundice is due to the accumulation of bilirubin in the blood, which causes the skin and whites of the eyes to turn yellow. Cholestasis is caused by obstruction of the flow of bile. **Possible Causes** 1. **Physiological jaundice of newborns**: Most newborns will experience mild jaundice in the first few days of life, which is a normal physiological phenomenon and will generally resolve on its own within 2 weeks. 2. Breast milk jaundice: Some breastfed babies develop jaundice 1-2 weeks after birth, usually because certain components of breast milk affect bilirubin metabolism. 3. Hepatobiliary diseases: such as bile duct atresia, hepatitis, etc., can lead to cholestasis and cause severe jaundice. 4. Genetic Disorders: Inherited metabolic disorders such as Hitling deficiency can also cause cholestasis and jaundice. **Care Recommendations** 1. **Regular monitoring**: Regularly check liver function and blood indicators, such as total bilirubin, direct bilirubin, white blood cells, red blood cells, etc., to keep abreast of changes in the condition. 2. **Medication**: Follow the doctor's instructions to use meropenem, diisopropylamine dichloroacetate, vitamin C and other drugs, while continuing to take glumalaloxone tablets, ursodeoxycholic acid, vitamin A, D and other drugs. 3. **Dietary modification**: With the advice of your doctor, consider whether you need to stop breastfeeding and switch to special formula to reduce the burden on the liver. 4. **Maintain Hygiene**: Keep your baby's skin clean, avoid infection, and change diapers and clothes in a timely manner. 5. **Regular check-up**: According to the doctor's advice, regularly perform imaging examinations such as B-ultrasound and MRI to understand the condition of the liver and gallbladder. Long-term high levels of total bilirubin can cause damage to the liver, so prompt treatment and care are required. The gradual decrease in red blood cells may be caused by infection or the influence of drugs, and the doctor should be communicated promptly to adjust the treatment plan. ### Epilogue Infant jaundice and cholestasis require close attention and joint efforts of parents and doctors to detect and deal with related problems in time to ensure the healthy growth of children.