### Common and Serious Side Effects of Dapagliflozin (Farxiga) ### Common Side Effects: - **Increased Urination**: You may find yourself peeing more often, including at night. This is because the drug helps remove excess glucose through urine. - **Cold-like Symptoms**: Some people experience a stuffy nose or sore throat. Over-the-counter medicines or home remedies like honey can help. - **Yeast Infections**: Extra sugar in urine can lead to yeast infections, especially in the genital area. Over-the-counter antifungal treatments can help, but see a doctor if symptoms persist. - **Dizziness**: This is more common when starting the medication. If you feel dizzy, rest and avoid driving or using machinery. - **Urinary Tract Infections (UTIs)**: Extra glucose in urine can also lead to UTIs. Symptoms include pain during urination and frequent urges to pee. ### Serious Side Effects: - **Dehydration**: Increased urination can lead to dehydration. Drink plenty of fluids, and seek medical help if you experience severe symptoms like dizziness or fainting. - **Low Blood Sugar (Hypoglycemia)**: This is more likely if you take another diabetes drug. Symptoms include shakiness and confusion. Monitor your blood sugar regularly. - **Allergic Reactions**: Symptoms can range from mild rashes to severe reactions like difficulty breathing. Seek immediate medical attention if you experience severe symptoms. - **Fournier’s Gangrene**: A rare but serious bacterial infection affecting the genital area. Symptoms include severe pain and swelling. Immediate medical attention is required. - **Ketoacidosis**: This condition occurs when your body uses fat instead of glucose for energy, leading to a buildup of acids called ketones. Symptoms include nausea and abdominal pain. Seek immediate medical care. - **Kidney Problems**: Some people may experience sudden kidney damage. Inform your doctor about any existing kidney issues before starting the medication. ### Combination Medications: - **Dapagliflozin and Metformin (Xigduo XR)**: May cause lactic acidosis, a condition where lactic acid builds up in the blood. - **Dapagliflozin and Saxagliptin (Qtern)**: May lead to pancreatitis, an inflammation of the pancreas. - **Dapagliflozin, Saxagliptin, and Metformin (Qternmet XR)**: Can cause serious side effects like heart failure and a rare skin condition called bullous pemphigoid. Always follow your doctor’s instructions and report any side effects you experience.