### Latest Treatments for Atopic Dermatitis Atopic dermatitis, also known as eczema, has seen significant advancements in treatment options. In the past, treatments often involved immune-suppressing drugs like oral steroids, which had serious side effects such as weight gain and high blood sugar. However, new treatments have emerged that target the underlying causes of the disease. **1. Crisaborole (Eucrisa):** This is the first phosphodiesterase-4 (PDE4) inhibitor approved by the FDA. It's a cream that reduces inflammation by blocking the enzyme PDE4. **2. Dupilumab (Dupixent):** This biologic drug targets proteins called cytokines (IL-4 and IL-13) that contribute to inflammation and itching. It's particularly safe for children and doesn't require regular blood tests. **3. Janus Kinase (JAK) Inhibitors:** These drugs block signals that prompt the immune system to produce more cytokines. They are available in pill form, making them convenient for those who prefer not to get injections. **4. New Topical Drugs:** Several new topical treatments are in development, including a topical JAK inhibitor and another PDE4 inhibitor that may be more potent than crisaborole. **5. Tapinarof:** This is the first in a new class of topical drugs called therapeutic aryl hydrocarbon receptor modulating agents (TAMA). It reduces inflammation and itching in a different way. **6. Skin Sprays with Healthy Bacteria:** These sprays introduce good bacteria to the skin, helping to fight off harmful bacteria and reduce inflammation. These new treatments offer hope for better management of atopic dermatitis, providing more options with fewer side effects.