### Prescription Medications for Atopic Dermatitis Atopic dermatitis, a common form of eczema, has no cure but can be managed with various treatments to reduce symptoms and control the disease. Here are the key prescription medications used: **Topical Medications:** - **Corticosteroids:** These are anti-inflammatory drugs applied to the skin to relieve itching and reduce inflammation. They come in different forms like ointments, creams, lotions, sprays, gels, and oils, and in various strengths. - **Topical Calcineurin Inhibitors (TCIs):** Nonsteroidal medications such as tacrolimus (Protopic) and pimecrolimus (Elidel) are used for sensitive areas like the face and genitals. - **PDE4 Inhibitors:** Crisaborole (Eucrisa) blocks an enzyme involved in inflammation, helping to clear the skin. - **JAK Inhibitors:** Ruxolitinib (Opzelura) reduces itch, rash, and redness by blocking specific enzymes involved in inflammation. **Oral Medications:** - **Systemic Immunosuppressants:** Drugs like cyclosporine, azathioprine, methotrexate, and mycophenolate mofetil suppress the immune system to stop the itch-scratch cycle. - **Oral Steroids:** Prednisone is used for short-term control of severe inflammation but can have serious side effects with long-term use. - **JAK Inhibitors:** Upadacitinib (Rinvoq) and abrocitinib (Cibinqo) block immune signals to reduce inflammation and itch. **Injectable Medications:** - **Biologics:** Dupilumab (Dupixent) and tralokinumab-ldrm (Adbry) are injected drugs that target specific proteins involved in the immune response, reducing symptoms significantly. **Other Treatments:** - **Antihistamines:** These can help relieve itching and inflammation, especially if allergies are a trigger. - **Over-the-Counter Pain Relievers:** Medications like acetaminophen, ibuprofen, and naproxen can help alleviate symptoms. Always consult with a healthcare provider to determine the best treatment plan for your specific condition.