### Understanding Erythrodermic Psoriasis Treatment Erythrodermic psoriasis is a rare and severe form of psoriasis that covers most of your body with a red, peeling rash. It can be painful, itchy, and cause a burning sensation. This condition is more common in people who already have another type of psoriasis. It can be triggered by certain medications, injuries, or severe sunburn. If not treated promptly, it can lead to serious health issues like dehydration, infections, or kidney failure. #### Hospitalization In severe cases, hospitalization may be necessary to monitor and manage the condition. #### Systemic Therapy Doctors often start with systemic therapy, which includes oral drugs or injections that suppress the immune system to reduce inflammation and slow down skin cell turnover. These medications can have serious side effects, so they are usually used for short periods. Common systemic medications include: - **Cyclosporine:** Often the first treatment for severe cases, taken daily for 12 to 16 weeks. - **Biologics:** Given as shots or IV infusions, used if other treatments fail. Infliximab (Remicade) is commonly used. - **Methotrexate:** An oral medication also used for arthritis, can cause stomach upset and long-term use may lead to liver damage. - **Acitretin (Soriatane):** A retinoid taken in pill form, can cause severe side effects including birth defects. - **Other Medications:** Thioguanine or hydroxyurea may be suggested if other treatments are ineffective. #### Additional Treatments - **Creams:** Topical steroids and vitamin D creams help reduce skin inflammation. - **Phototherapy:** Uses low-dose UV light to calm inflammation, often recommended as a long-term treatment after initial control with systemic therapy. #### Home Care Tips - **Bathing:** Take baths daily to remove scales and soothe the skin. Use bath oils, salts, or colloidal oatmeal, and avoid harsh soaps and hot water. - **Moisturizing:** Keep your skin moisturized to prevent dryness, which can worsen psoriasis. Use heavy moisturizing ointments or oils after bathing. - **Humidifier:** Use a humidifier to keep the air moist, especially during dry winter months. - **Sun Exposure:** Small amounts of sunlight can improve psoriasis. Consult your doctor for safe sun exposure guidelines and use sunscreen on unaffected areas to reduce skin cancer risk. Always follow your doctor's treatment plan and report any side effects. Avoid triggers like alcohol, smoking, and stress to help manage the condition.