What are the types and causes of lupus?
Lupus is an autoimmune disease where the immune system attacks the body's own tissues. It affects people of African, Asian, or Native American descent more often than whites, and 90% of those affected are women. Lupus usually appears between ages 15 and 44. There are two main types of lupus: Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE). DLE mainly affects skin exposed to sunlight and can leave scars. SLE is more serious, affecting the skin and vital organs, and can cause a butterfly-shaped rash on the face. SLE can also damage joints, muscles, and organs like the lungs, heart, kidneys, and brain. It can cause kidney disease, confusion, depression, seizures, and strokes. Blood vessels may also be affected, leading to sores on the skin and Raynaud's syndrome, which causes pain and color changes in the hands and feet. The exact cause of lupus is unknown, but it may involve genetic, hormonal, environmental, and immune system factors. Triggers can include infections, stress, sunlight, and certain drugs. High estrogen levels, such as during pregnancy, may worsen lupus.