Skin disease treatments can have strong side effects, but there are ways to manage them. It's important to communicate with your doctor about any problems you're experiencing so they can adjust your treatment plan. Here are some common side effects and tips to help you manage them: **Fatigue:** Many people feel very tired during their treatment. Regular, gentle exercise like yoga or brisk walking can help boost your energy levels. Always consult your doctor before starting any exercise routine. **Nausea:** Anti-nausea medications can be prescribed by your doctor. Dietary changes, such as eating smaller, more frequent meals, can also help. **Skin Issues:** Treatments can cause rashes, dry skin, or hand-foot syndrome. Use thick, fragrance-free emollient creams several times a day and consider wearing socks or gloves at night. Vitamin B6 supplements may also help. If these measures don't work, your doctor may adjust your dosage or prescribe additional medications. **Peripheral Neuropathy:** This is a side effect of some treatments that causes numbness or tingling in your hands and feet. Inform your doctor immediately if you experience these symptoms. They may adjust your medication or prescribe something to help. **Mouth Sores:** Some treatments can cause painful sores in your mouth, making it hard to eat or drink. Your doctor can recommend special mouthwashes or medications to ease the pain. **Lymphedema:** If you've had lymph nodes removed, you may experience swelling in your arms or legs. Avoid cuts, burns, and muscle strain on the affected side. A specially trained physical therapist can provide compression garments and exercises to reduce swelling. **Hair Loss:** Some treatments cause hair loss. You can choose to wear wigs, scarves, or hats, or go without. Wigs may be tax-deductible and covered by health insurance with a doctor's prescription. Always keep your healthcare provider informed about your side effects so they can help you manage them effectively.