### What is Histamine and How Does it Affect You? Histamine is a natural chemical in your body that helps cells communicate. It plays several important roles, including managing your sleep cycle and supporting brain function. However, it is best known for its role in allergic reactions. ### How Does Histamine Work? When your immune system detects a potential allergen like pollen or mold, it may overreact and release histamine from mast cells (a type of white blood cell). This histamine release triggers an allergic reaction, causing symptoms like coughing, wheezing, and watery eyes. ### Histamine Intolerance Some people have a condition called histamine intolerance, where their bodies can't break down histamine properly. This leads to a buildup of histamine, causing allergy-like symptoms such as headaches, stomach upset, and low blood pressure. About 1% of the population has this condition, which is more common in middle age. ### Symptoms of High Histamine Levels High histamine levels can cause various symptoms, including: - Stuffy or runny nose - Headaches - Stomach upset - Low blood pressure In severe cases, it can lead to anaphylaxis, a dangerous condition that requires immediate medical attention. ### Foods and Medications Certain foods and medications can raise histamine levels. Foods like aged cheeses, processed meats, and fermented products are high in histamine. Some medications can also interfere with histamine breakdown. ### Managing Histamine Intolerance The main treatment for histamine intolerance is a change in diet. Avoiding high-histamine foods and opting for fresh, whole foods can help manage symptoms. Keeping a food diary and consulting a registered dietitian can also be beneficial. ### Conclusion Histamine is crucial for many bodily functions but can cause problems when levels are too high. If you suspect you have histamine intolerance, consult your doctor for proper diagnosis and treatment.