### What is Eptinezumab (Vyepti)? Eptinezumab (Vyepti) is a medication prescribed by doctors to help prevent migraines. Migraines are severe headaches that can disrupt your daily life. ### How Does It Work? Eptinezumab is a monoclonal antibody that targets a protein called calcitonin gene-related peptide (CGRP). CGRP can cause inflammation and pain in the brain. By blocking CGRP, eptinezumab helps to reduce the likelihood of migraines. ### How is it Administered? You receive eptinezumab through an IV (intravenous) infusion in your doctor’s office. Each session takes about 30 minutes, and you get it once every 3 months. ### Common Side Effects - Stuffy nose and scratchy throat: These are the most common side effects, reported by fewer than 1 in 12 people. - Allergic reactions: Rare but can include itching, hives, rash, or redness at the IV site. Severe reactions like throat swelling or trouble breathing are very rare. ### Precautions - Heart attack or stroke: If you’ve had either recently, you should not take eptinezumab. - Allergic reactions: If you’ve had an allergic reaction to eptinezumab before, avoid taking it again. - Pregnancy and breastfeeding: Consult your doctor as there is limited information on its safety. ### Drug Interactions Eptinezumab is generally safe to take with other medications, but always inform your doctor about all the drugs you are taking, including over-the-counter medicines, vitamins, and herbal supplements. ### Effectiveness Clinical trials have shown that eptinezumab can reduce the number of migraine days per month for both episodic and chronic migraine sufferers. Some people experience relief within the first week of treatment. ### Monitoring Keep track of your migraine days and discuss them with your doctor to determine if eptinezumab is effective for you.