What should you know about scopolamine, including its sources, uses, and side effects?

### What is Scopolamine? Scopolamine, also known as Devil's Breath, is a naturally occurring compound found in several plants like Brugmansia (Angel's Trumpet), Datura stramonium (Jimsonweed), Scopolia carniolica, and Hyoscyamus niger (henbane). These plants produce toxic belladonna alkaloid compounds as a form of self-defense. ### Uses of Scopolamine Scopolamine is used in the medical field to treat various conditions such as nausea, vomiting, motion sickness, and muscle spasms. It is particularly effective in treating postoperative nausea and vomiting (PONV). The World Health Organization (WHO) lists scopolamine as an essential medicine due to its effectiveness and low cost. ### How is it Administered? The most common method of administering scopolamine is through a transdermal patch, usually applied behind the ear. The patch takes a few hours to start working and is often used before surgery to prevent nausea. It should be kept on for 24 hours after surgery and can be worn for up to 3 days if nausea persists. ### Common Side Effects While scopolamine is effective, it can cause side effects such as dry mouth, dizziness, blurred vision, and confusion. These symptoms usually go away once the patch is removed. However, more serious side effects like hallucinations, severe confusion, and difficulty urinating require immediate medical attention. ### Recreational Use and Dangers Scopolamine has a history of being used for criminal purposes. In some parts of the world, it is used to incapacitate victims. Recreational use can lead to severe hallucinations, a hypnotized state, and even death. Just a gram of scopolamine powder can be lethal. ### Conclusion Scopolamine is a powerful drug with both medical benefits and potential dangers. It should only be used under professional medical supervision to avoid serious side effects and risks.