### What Are SGLT2 Inhibitors? SGLT2 inhibitors are a new class of oral medications used to treat type 2 diabetes. Examples include Farxiga (dapagliflozin) and Jardiance (empagliflozin). These drugs help lower blood sugar levels by causing the kidneys to remove sugar through urine. ### How Do They Work? SGLT2 inhibitors work by blocking a protein in the kidneys called SGLT2. This protein helps reabsorb glucose back into the blood. By blocking this protein, the drugs cause more glucose to be excreted in the urine, thus lowering blood sugar levels. ### Benefits - **Lower Blood Sugar**: Helps manage blood sugar levels without the need for insulin. - **Heart and Kidney Health**: Can improve heart and kidney health, reducing the risk of complications like heart failure and advanced kidney disease. - **Weight Loss**: May help with weight loss and reduce waist circumference. - **Blood Pressure**: Can also help lower blood pressure. ### Who Should Consider Them? - **Uncontrolled Blood Sugar**: If your blood sugar levels are not well-controlled with metformin and lifestyle changes, SGLT2 inhibitors might be an option. - **Heart or Kidney Issues**: If you have heart disease, heart failure, or kidney disease, these drugs may offer additional benefits. ### Side Effects Common side effects include urinary tract infections and increased urination. More serious side effects can include dehydration and kidney issues. Always discuss potential side effects with your doctor. ### Conclusion SGLT2 inhibitors offer a promising option for managing type 2 diabetes, especially for those who have not achieved desired blood sugar levels with other treatments. Consult your doctor to see if these medications are right for you.