Can depression increase the risk of stroke and affect recovery?

### Depression and Stroke: What You Need to Know Recent research has shown that people with depression may face a higher risk of having a stroke and more difficulties in recovering from one. The INTERSTROKE study, published in the journal *Neurology*, involved about 27,000 participants from 32 countries. The average age of the participants was 62, and about half of them had experienced a stroke. These individuals were compared to similar people who had not had a stroke. Participants answered questionnaires about various heart disease risk factors, such as high blood pressure and diabetes, as well as symptoms of depression. The study found that 18% of participants who had a stroke also had symptoms of depression, compared to 14% of those who had not had a stroke. After adjusting for factors like age, sex, education, physical activity, and other lifestyle factors, researchers found that people with symptoms of depression before a stroke had a 46% increased risk of having a stroke compared to those without depression symptoms. The risk was even higher for those with more symptoms of depression; individuals reporting five or more symptoms had a 54% higher risk of stroke. The study's lead author, Robert P. Murphy from the University of Galway in Ireland, emphasized that depressive symptoms are a significant risk factor for both ischemic and hemorrhagic strokes. He noted that these symptoms not only impact mental health but also increase the risk of stroke. Murphy suggested that physicians should be vigilant in identifying symptoms of depression and use this information to guide health initiatives focused on stroke prevention.