### How Common Medications Can Affect Your Heart Health Heart failure is a condition where your heart doesn't pump blood as well as it should. This can lead to symptoms like shortness of breath, weakness, and swollen legs and feet. While heart disease and diabetes are common causes, certain medications can also increase your risk of heart failure. Here are some key points to keep in mind: #### Medications That Can Affect Heart Health - **Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)**: These include prescription drugs like diclofenac, ibuprofen, indomethacin, and ketorolac. They can cause water and salt retention, making it harder for your blood to flow and for diuretic drugs to work. - **Diabetes Medications**: Metformin is not ideal if your kidneys are not functioning well. Thiazolidinediones (pioglitazone, rosiglitazone) can cause fluid retention and weight gain, increasing the risk of heart failure. Dipeptidyl peptidase-4 inhibitors (alogliptin, linagliptin, saxagliptin, sitagliptin) have also been linked to increased hospitalizations for heart failure. - **Blood Pressure Medications**: Calcium channel blockers can worsen edema. Central agonists (clonidine, moxonidine) can alter hormone release, affecting your heart. #### Over-the-Counter (OTC) Medications - **NSAIDs**: Even OTC NSAIDs can worsen heart failure and increase the likelihood of hospitalization. - **Cold Medicines**: Some contain NSAIDs or sodium, which can worsen heart failure. Nasal decongestants often have vasoconstrictors that narrow blood vessels, potentially causing heart problems. #### Natural Supplements and Vitamins - **Supplements**: These are not regulated by the government, so their contents can be uncertain. Some can interact with heart medications like digoxin and blood thinners. - **Vitamins**: High doses of vitamins, like more than 400 IU of vitamin E daily, can increase the risk of heart failure. #### Tips for Managing Medications and Supplements - Always consult your doctor before stopping any medication. - Ask your doctor for a list of safe OTC drugs and what to look for on labels. - Inform your healthcare team about all the drugs and supplements you take to minimize risks. By being aware of these potential risks and working closely with your healthcare team, you can better manage your heart health, especially if you have diabetes.