How do alpha-glucosidase inhibitors like Precose and Glyset help manage type 2 diabetes, what are their side effects, and who should avoid them?

Alpha-glucosidase inhibitors, such as acarbose (Precose) and miglitol (Glyset), are medications used to treat type 2 diabetes. They work by slowing down the breakdown of starchy foods and some sugars, which helps prevent blood sugar levels from rising too quickly after meals. These medications are usually taken with the first bite of each meal, three times a day. They can lower your A1c by about 0.5% to 0.8%. Common side effects include gas, bloating, and diarrhea, which typically subside after a few weeks. However, these drugs are not suitable for everyone. People with certain conditions like inflammatory bowel disease, colonic ulceration, or partial intestinal obstruction should avoid them. They are also not recommended for pregnant women. Always consult your doctor to determine if these medications are right for you.