### How Rexulti Helps in Managing Alzheimer's Disease Dementia Rexulti is a third-generation antipsychotic medication that is used to manage symptoms of agitation and aggression in people with Alzheimer's disease dementia. These symptoms can be very challenging and may include verbal or physical aggression and restlessness. Rexulti works by increasing the levels of dopamine and serotonin in the brain, which can help improve mood and behavior. #### Dosage and Administration Rexulti is taken as an oral tablet once daily, with or without food. The starting dose is usually 0.5 milligrams per day and can be increased based on your response and other factors like drug interactions and liver or kidney function. The maximum dose is 3 milligrams per day. It is important to follow your healthcare provider's instructions on how to start and adjust the dose. #### Effectiveness Two 12-week studies have shown that Rexulti can help reduce symptoms of agitation in people with Alzheimer's disease dementia. In these studies, people taking Rexulti showed a decrease in aggressive or agitated symptoms compared to those taking a placebo. This means that consistent use of Rexulti can help improve daily functions over time. #### Side Effects Common side effects of Rexulti include weight gain, sleepiness, dizziness, cold-like symptoms, and restlessness. It is important to monitor your weight, blood pressure, cholesterol levels, and blood sugar levels while taking this medication. Healthy lifestyle choices such as exercising, eating more vegetables and fruits, and limiting unhealthy fats can help prevent weight gain. #### Precautions Rexulti may cause dizziness or sleepiness, which can lead to falls. If you experience dizziness, avoid sudden movements. If you feel sleepy, consider taking your dose in the evening. Avoid driving or doing tasks that require alertness until you know how Rexulti affects you. Rexulti may also cause restlessness, which can be managed with regular exercise and activities that calm the brain, like meditation or light yoga. #### Monitoring and Interactions Your healthcare provider may do lab tests to monitor your health and see how your body responds to the medication. Several medicines can affect the blood levels of Rexulti, so it's important to tell your healthcare provider about all the medications and supplements you are taking. #### Cost and Savings There is a copay program from the drugmaker that may allow you to pay $0 for your prescription, depending on your insurance. You can find more information at the Rexulti website. Always consult your healthcare provider before making any changes to your medication regimen.