### The Role of ACE2 in Diabetes and COVID-19 People with diabetes are more prone to complications, and recent studies suggest a link between diabetes and severe COVID-19 symptoms. One enzyme, angiotensin converting enzyme 2 (ACE2), is often overactive in people with diabetes and may partly explain this increased risk. #### What is ACE2? ACE2 is an enzyme that helps regulate several critical functions in the body. It plays a major role in the renin-angiotensin-aldosterone system (RAAS), which controls blood pressure, inflammation, and other vital processes. #### ACE2 and Diabetes In people with diabetes, especially those with diabetes-related kidney disease, ACE2 levels are often elevated. This overactivity can lead to complications like high blood pressure, cardiovascular disease, and kidney disease. #### ACE2 and COVID-19 The virus causing COVID-19, SARS-CoV-2, binds to ACE2 receptors to enter the body. In people with diabetes, the elevated ACE2 levels provide more entry points for the virus, potentially leading to more severe symptoms. Studies have shown that people with diabetes are at higher risk of severe illness and death from COVID-19. #### Why is This Important? Understanding the role of ACE2 can help explain why people with diabetes face higher risks from COVID-19. It also highlights the importance of managing blood glucose levels and protecting against infections. #### Conclusion If you have diabetes, talk to your healthcare provider about how to manage your condition and protect yourself from infections like COVID-19.