How does type 2 diabetes affect the risk and prognosis of endometrial cancer in women?

### How Type 2 Diabetes Affects Endometrial Cancer Risk and Prognosis A recent study has found that women with type 2 diabetes have a higher risk of dying from endometrial cancer. This is significant because gynecological cancers, including stage I endometrial cancer, can often be successfully treated with surgery. Endometrial cancer is the most common type of uterine cancer, and more than 66,000 women in the U.S. are expected to be diagnosed with it in 2023. #### Risk Factors Risk factors for endometrial cancer include family history, obesity, early menstruation, late menopause, never having been pregnant, previous breast or ovarian cancer, and taking hormonal replacement therapy. Lynch syndrome, a genetic mutation, also increases risk. Women with type 2 diabetes have a 62% higher chance of developing endometrial cancer. Insulin resistance, common in type 2 diabetes, may encourage cancer cell growth. #### Symptoms Symptoms of endometrial cancer include abnormal vaginal bleeding, pelvic pain, and weight loss. As the cancer advances, symptoms can worsen. Type 2 diabetes symptoms include increased thirst, frequent urination, and fatigue. #### Prevention Preventive measures include regular checkups, genetic testing, and lifestyle changes. Moderate exercise and a low glycemic index diet can help manage blood sugar levels. Medications that improve insulin sensitivity may also be beneficial. #### Conclusion Women with type 2 diabetes should be vigilant about their health and consult their doctors for regular screenings and preventive strategies. Early detection and lifestyle changes can significantly improve outcomes.