How have new diabetes medications that also address obesity influenced the latest guidelines from the American Diabetes Association?

### New Diabetes Guidelines and Medications The American Diabetes Association (ADA) has released the 2023 Standards of Care in Diabetes, which are updated annually to reflect the latest research. This year, the guidelines focus on more aggressive treatment of diabetes and reducing complications, with new recommendations on weight loss, blood pressure, cholesterol, and more. #### Weight Loss Goals The new guidelines emphasize higher weight loss goals—up to 15% of body weight—especially for those who have access to newer medications and respond well to them. Previously, a 5% weight loss was recommended, but greater weight loss can significantly reduce illness and death. New medications like GLP-1 receptor agonists (e.g., Ozempic, Wegovy) and SGLT2 inhibitors (e.g., Jardiance, Farxiga) have shown to be effective in both glycemic and weight management. #### Blood Pressure and Cholesterol The new guidelines also lower the target for blood pressure to less than 130/80, aligning with recommendations from the American Heart Association. For LDL cholesterol, the target is now less than 70 for those with diabetes and cardiovascular risk factors, and even lower (55 or less) for those with established heart disease. #### Sleep and Exercise The guidelines highlight the importance of sleep quality and duration, as poor sleep can negatively impact blood glucose levels and obesity risk. Screening for sleep issues is recommended. Exercise is also emphasized, with a recommendation of 150 minutes of physical activity per week, spread over at least three sessions. Even modest increases in activity can be beneficial. #### Social Determinants of Health The guidelines recognize that not everyone has equal access to healthcare, medications, or healthy lifestyle options. Screening for food and housing insecurity and financial barriers is recommended to identify at-risk patients. #### Additional Updates The new standards also include updates on technology, kidney disease prevention, and preventing amputations. People with diabetes are encouraged to discuss these new guidelines with their healthcare providers to ensure their treatment plans are up-to-date.