Is there a link between polycystic ovary syndrome (PCOS) and early cognitive decline?

### Polycystic Ovary Syndrome (PCOS) and Cognitive Decline Polycystic ovary syndrome (PCOS) is a common condition that affects more than 1 in 10 women and is a leading cause of infertility. Women with PCOS often experience irregular menstrual cycles, excess hair growth, and ovarian cysts. They are also at a higher risk for type 2 diabetes, heart disease, high blood pressure, cholesterol problems, and sleep apnea, especially if they are overweight. Recent research has explored the potential link between PCOS and brain health. A study published in the journal Neurology found that women with PCOS symptoms may experience lower memory and thinking skills as they age. The study followed 907 women over 30 years, starting when they were between 18 and 30 years old. By the end of the study, the women were tested on memory, verbal abilities, attention, and processing speed. The results showed that women with PCOS symptoms scored lower on cognitive tests. For example, they scored about 11% lower on an attention test that required them to identify the color of ink rather than read the word itself. They also had lower scores on memory and verbal ability tests. Additionally, MRI scans revealed changes in the white matter of their brains, which could be a sign of early brain aging. While the study did not prove that PCOS causes cognitive decline, it did find a consistent link between the two conditions. The researchers emphasized the need for further studies to confirm these findings and to explore ways to reduce the risk of cognitive decline in women with PCOS. They suggested that lifestyle changes, such as increased cardiovascular exercise and improved mental health, might help improve brain aging in this population.