### Late-Stage Multiple Myeloma: Complications and Survival Rates Late-stage multiple myeloma, also known as stage III, is a serious condition where cancer cells have spread to different parts of the body. This stage is often diagnosed late because the disease can start without symptoms. By the time symptoms appear, the cancer may have already spread and caused damage to organs. #### Common Complications 1. **Hypercalcemia**: As the cancer speeds up bone breakdown, large amounts of calcium can enter the bloodstream, leading to symptoms like nausea, vomiting, and confusion. In severe cases, it can cause coma. 2. **Peripheral Neuropathy**: Damage to nerves can cause a “pins and needles” sensation. 3. **Kidney Problems**: High levels of creatinine in the blood can indicate poor kidney function. 4. **Infections**: People with multiple myeloma are more likely to get infections. Pneumonia is a common cause of infection-related deaths. #### Survival Rates There is no cure for multiple myeloma, but treatments can help manage symptoms. The 5-year relative survival rate for stage III multiple myeloma is about 53%. Factors like kidney function, age, and overall health can influence survival chances. #### Managing the Condition - **Vaccinations**: The CDC recommends getting influenza, shingles, and pneumococcal vaccines. - **Supportive Care**: Palliative care doctors, social workers, and chaplains can help manage emotional and mental health. - **Daily Activities**: Challenges in daily activities can cause stress, but resources are available to help. If you have stage III multiple myeloma, talk to your doctor to understand your condition and treatment options better.