### Understanding Mounjaro, Ozempic, Wegovy, and Zepbound Mounjaro, Ozempic, Wegovy, and Zepbound are medications used to manage type 2 diabetes and aid in weight loss. Here's a breakdown of how they work, their benefits, and side effects: #### How They Work - **Mounjaro and Zepbound**: Both contain tirzepatide, which acts as a GLP-1 and GIP receptor agonist. These hormones help regulate blood sugar and slow down stomach emptying, making you feel full longer. - **Ozempic and Wegovy**: Both contain semaglutide, a GLP-1 receptor agonist. It works similarly by mimicking a hormone that helps control blood sugar and appetite. #### Benefits - **Blood Sugar Control**: All four medications help manage blood sugar levels in people with type 2 diabetes. - **Weight Loss**: They can aid in weight loss by reducing appetite and slowing stomach emptying. Clinical trials show that tirzepatide (Mounjaro, Zepbound) may lead to more weight loss compared to semaglutide (Ozempic, Wegovy). #### Side Effects - **Common Side Effects**: Nausea, vomiting, diarrhea, and constipation are common with all four medications. - **Specific Concerns**: Long-term effects are still being studied, and these medications can be costly. They may not be suitable for people with a history of pancreatitis or those who are pregnant. #### Usage - **Mounjaro and Zepbound**: Typically used for type 2 diabetes and weight management in adults with a BMI of 30 or more, or 27 with another health condition. - **Ozempic and Wegovy**: Ozempic is primarily for type 2 diabetes, while Wegovy is approved for weight management in adults and children 12 and older with obesity. #### Dosage - **Mounjaro and Zepbound**: Start at 2.5 mg per week, increasing up to 15 mg as needed. - **Ozempic and Wegovy**: Start at a lower dose and gradually increase. Wegovy can go up to 2.4 mg per week. #### Cost and Insurance - These medications can cost around $1,000 per month without insurance. Coverage may vary based on the specific medication and its approved use. ### Conclusion Consult your doctor to determine which medication is best for you based on your health needs, weight loss goals, and insurance coverage.