Peripheral artery disease (PAD) causes inflammation in the blood vessel walls, reducing blood flow to your limbs. Some supplements might help, while others could be harmful. Always consult your doctor before starting any new supplement. Beneficial supplements include Omega-3 fatty acids, which may lower triglycerides; Berberine, which has anti-inflammatory effects and can help regulate glucose metabolism; Ground flaxseed, which may lower LDL cholesterol; Green tea, which might also lower LDL cholesterol; Niacin, which can improve HDL cholesterol; Plant stanols and sterols, which reduce LDL cholesterol; and Fiber, which helps remove cholesterol from your body. Harmful or less beneficial supplements include Potassium, which can cause dangerous heart rhythms if not balanced; Magnesium, which can cause diarrhea if taken in excess; Chromium, which should be avoided if you have kidney disease; Vitamin C, which might increase cardiovascular risk in high doses; Vitamin D, which might cause calcium deposition in blood vessels if levels are normal; Vitamin E, which can increase bleeding risk if you're on blood thinners; Folate and other B vitamins, which might be harmful if you have kidney disease; and Calcium, which should be obtained from food rather than supplements to avoid heart disease risk.