Yes, osteoporosis increases the risk of prosthesis loosening. Osteoporosis makes bones weak and porous, which means they have a reduced ability to withstand weight or pressure. When a prosthesis is implanted, it needs to be securely anchored to the bone. If the bone is not strong enough, the prosthesis is more likely to loosen. Therefore, preventing and treating osteoporosis is very important for those who need prostheses.