Creatine is a substance found mostly in your muscles and brain. While small amounts can be obtained from seafood and red meat, larger amounts are found in supplements. It helps improve exercise performance and may benefit older adults by increasing muscle mass and bone density, reducing the risk of falls and fractures. Creatine might also help with type 2 diabetes and certain neurological diseases. Topical creams with creatine can reduce skin aging. It's considered safe for seniors in high doses for short periods, but you should consult a doctor first. Possible side effects include weight gain and interactions with caffeine. The FDA doesn't regulate creatine supplements, so product quality can vary.