Cortisone injections, also known as corticosteroid shots, are used to reduce inflammation in the body. They are commonly used to treat conditions like arthritis, back pain, bursitis, gout, osteoarthritis, and tendinitis. These injections can quickly relieve inflammation in specific areas like a knee or elbow. Short-term side effects are rare but can include skin changes, infection, bleeding, and soreness at the injection site. Long-term side effects depend on the dose and frequency and can include skin thinning, easy bruising, weight gain, puffy face, high blood pressure, cataracts, and osteoporosis. The injection process involves cleaning the skin, numbing the area, and then administering the shot. The effects can last for several months, but doctors typically limit injections to once every 6 weeks and no more than four times a year. After the injection, it's common to feel warmth or redness around the site, and doctors often recommend using an ice pack and avoiding strenuous activity for a couple of days. If signs of infection, pain, or swelling persist after two days, you should contact your doctor.