Hormone therapy for prostate cancer has made significant advancements over the years. Initially, the only option was orchiectomy, a surgical procedure to remove the testicles. Today, there are various medications available in pills, injections, and implants that reduce male hormone levels without surgery. Hormone therapy is used mainly for cancer that has recurred or spread. While it doesn't cure cancer, it can slow its growth and improve quality of life. About 85-90% of advanced cases respond well, but the therapy doesn't work forever as some cancer cells don't rely on hormones. Side effects include bone thinning, which can lead to osteoporosis, but medications like bisphosphonates can help. Researchers continue to explore the best combinations and timing for hormone therapy, including intermittent and early treatments. Though hormone therapy alone may not be the ultimate solution, it continues to play a vital role in managing prostate cancer.