Hormone therapy for breast cancer, such as tamoxifen and aromatase inhibitors, can help prevent cancer from returning. These medications are prescribed for hormone-positive tumors, which account for about two-thirds of breast cancers. While they are very effective, they can have side effects. Common side effects include hot flashes, night sweats, and vaginal dryness. Environmental changes like keeping your room cool can help with hot flashes and night sweats. Over-the-counter lubricants can help with vaginal dryness. Joint pain and bone loss are also possible, especially with aromatase inhibitors. Regular exercise and vitamin D supplements can help manage these issues. In rare cases, tamoxifen can cause blood clots and increase the risk of uterine cancer. If you experience severe side effects, talk to your doctor, who may suggest switching medications. Never stop taking your medication without consulting your doctor, as this could increase the risk of cancer recurrence.