Prolia and Xgeva are prescription drugs used for osteoporosis and other conditions. Both help prevent fractures, but they are used for different types of cancer. Prolia is mainly used to prevent fractures in patients with prostate or breast cancer, while Xgeva is used for patients with bone cancer caused by solid tumors or multiple myeloma. Both drugs contain the same active ingredient, denosumab, but Prolia is not approved for use in children, whereas Xgeva can be used in children whose bones have stopped growing. Both drugs may cause mild or serious side effects, and detailed information can be obtained by consulting a doctor.