Adult-onset Still’s disease is a rare type of arthritis that starts in adulthood, causing fever, rash, and joint pain. While the exact cause is unknown, it may be triggered by infections or toxins, leading the immune system to overreact. Symptoms can come and go, including fever, rash, and joint pain, often in the wrists and knees. In severe cases, it can cause swollen organs or inflammation in the heart or lungs. Diagnosis involves ruling out other conditions with blood tests and imaging. Treatment focuses on managing symptoms with NSAIDs, steroids, methotrexate, and biologic response modifiers. Regular exercise, a healthy diet, and possibly supplements like vitamin D and calcium are recommended. Early diagnosis and treatment can improve outcomes, though some may experience chronic arthritis. Staying connected with specialists and support organizations is beneficial.