Bone pain usually feels deeper, sharper, and more intense than muscle pain. Muscle pain is often spread throughout the body, appearing after exercise or illness, and usually eases within a few days. Joint pain commonly affects ankles, knees, or elbows, and may be caused by arthritis or aging. Bone pain is more focused and lasts longer, and should always be taken seriously. Common causes of bone pain include: fractures (possibly from trauma or overuse), osteoporosis (leading to decreased bone density and painful fractures), cancer (which may be bone metastasis or primary bone cancer), sickle cell disease (lack of red blood cells causing bone damage and severe pain), infection (osteomyelitis, which may spread from other body parts to the bone), and pregnancy-related pelvic pain. Treatment for bone pain depends on its cause, for instance, fractures may need casting or splinting, osteoporosis-related pain can be managed with medications and lifestyle changes, osteomyelitis requires antibiotics, cancer-related pain treatment is complex, sickle cell disease pain can be treated with various medications, and pregnancy-related pelvic pain can be alleviated with physical therapy and exercises. No matter the cause, significant bone pain requires medical attention. Maintaining healthy bones is key to preventing bone pain.