Patients with rheumatoid arthritis (RA) may experience other chronic conditions besides joint problems. Common conditions include cardiovascular disease, obesity, diabetes, depression, and lung diseases such as asthma, COPD, and interstitial lung disease. RA shares risk factors with these diseases, like smoking. Some RA medications, such as glucocorticoids, can reduce inflammation but also raise blood sugar levels, increasing the risk of diabetes. RA can also affect the quality of life by limiting daily activities, leading to mental health issues. The relationship between RA and these conditions is bidirectional. For example, depression and anxiety can worsen RA symptoms, and RA inflammation can impact mental health. Comprehensive management of RA and other chronic conditions is crucial for long-term health. RA patients often need multiple specialists to collaborate, especially a good primary care provider to coordinate treatments. For osteoporosis, RA inflammation and glucocorticoid treatment can accelerate bone loss, so regular bone density scans and supplements of calcium and vitamin D are necessary.