Middle-aged and older adults need regular vaccinations and screening tests to stay healthy. People aged 50 and older should get the Shingrix shingles vaccine, even if they have previously received Zostavax. It is also important to get a flu shot every year, and those over 65 can opt for the Fluzone High-Dose vaccine or Fluad. Adults 65 and older should also receive two pneumococcal vaccines, PCV13 and PPSV23, a year apart. Every ten years, a Tdap booster shot is needed. As for screening tests, individuals aged 45 and older should undergo colon cancer screening and type 2 diabetes screening every three years starting at age 45. Those at higher risk for osteoporosis should have a bone density test. Comprehensive eye exams are recommended every 2 to 4 years after age 50 and possibly annually after age 55. Blood pressure and cholesterol should be checked regularly. Women should have annual mammograms starting at age 45, switching to every two years at age 55, and stopping after age 75. Cervical cancer screening can be done every three years with a Pap test or every five years with an HPV test. Men should consider PSA testing for prostate cancer based on their risk levels.